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Table 4 FDG ROI Z score and lateralization index comparisons

From: Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography

  CBS-PIB + (number = 10) CBS-PIB-(number = 12) NC (number = 26) P Post hoc
FDG-common, z −1.89 ± 0.81 −1.69 ± 1.37 0.00 ± 1.00 0.000 CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.001
right −2.29 ± 0.89 −1.48 ± 1.66 0.00 ± 1.00 0.000 CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.01
left −1.59 ± 0.91 −1.91 ± 1.30 0.00 ± 1.00 0.000 CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.001
LI 10.42 ± 4.37 8.82 ± 5.99 2.83 ± 1.72 0.000 CBS- PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.014
FDG-frontal, z −1.26 ± 0.91 −1.06 ± 1.61 0.00 ± 1.00 0.005 CBS-PIB+ versus NC P <0.05, CBS-PIB- versus NC P <0.05
right −1.51 ± 0.94 −0.83 ± 1.55 0.00 ± 1.00 0.002 CBS-PIB+ versus NC P <0.01
left −1.00 ± 0.92 −1.30 ± 1.84 0.00 ± 1.00 0.008 CBS-PIB- versus NC P <0.05
LI 6.53 ± 3.08 10.52 ± 8.16 1.70 ± 1.33 0.000 CBS- PIB+ versus NC P <0.002, CBS-PIB- versus NC P <0.008
FDG-temporoparietal, z −2.76 ± 1.65 −0.93 ± 1.65 0.00 ± 1.00 0.000 CBS-PIB+ versus CBS-PIB- P <0.01, CBS-PIB+ versus NC P <0.001
right −3.22 ± 2.12 −0.65 ± 1.84 0.00 ± 1.00 0.000 CBS-PIB+ versus CBS-PIB- P <0.05, CBS-PIB+ versus NC P <0.05
left −2.20 ± 1.38 −1.06 ± 1.56 0.00 ± 1.00 0.000 CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.05
LI 13.10 ± 8.20 8.45 ± 6.95 2.00 ± 1.41 0.000 CBS- PIB+ versus NC P <0.005, CBS-PIB- versus NC P <0.021
  1. CBS-PIB+, corticobasal syndrome positive for Pittsburgh compound B; CBS-PIB-, corticobasal syndrome negative for Pittsburgh compound B; FDG, fluorodeoxyglucose; LI, lateralization index; NC, normal control; ROI, region of interest. Data are mean ± standard deviation.
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Alzheimer's Research & Therapy

ISSN: 1758-9193