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Table 4 FDG ROI Z score and lateralization index comparisons

From: Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography

 

CBS-PIB + (number = 10)

CBS-PIB-(number = 12)

NC (number = 26)

P

Post hoc

FDG-common, z

−1.89 ± 0.81

−1.69 ± 1.37

0.00 ± 1.00

0.000

CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.001

right

−2.29 ± 0.89

−1.48 ± 1.66

0.00 ± 1.00

0.000

CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.01

left

−1.59 ± 0.91

−1.91 ± 1.30

0.00 ± 1.00

0.000

CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.001

LI

10.42 ± 4.37

8.82 ± 5.99

2.83 ± 1.72

0.000

CBS- PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.014

FDG-frontal, z

−1.26 ± 0.91

−1.06 ± 1.61

0.00 ± 1.00

0.005

CBS-PIB+ versus NC P <0.05, CBS-PIB- versus NC P <0.05

right

−1.51 ± 0.94

−0.83 ± 1.55

0.00 ± 1.00

0.002

CBS-PIB+ versus NC P <0.01

left

−1.00 ± 0.92

−1.30 ± 1.84

0.00 ± 1.00

0.008

CBS-PIB- versus NC P <0.05

LI

6.53 ± 3.08

10.52 ± 8.16

1.70 ± 1.33

0.000

CBS- PIB+ versus NC P <0.002, CBS-PIB- versus NC P <0.008

FDG-temporoparietal, z

−2.76 ± 1.65

−0.93 ± 1.65

0.00 ± 1.00

0.000

CBS-PIB+ versus CBS-PIB- P <0.01, CBS-PIB+ versus NC P <0.001

right

−3.22 ± 2.12

−0.65 ± 1.84

0.00 ± 1.00

0.000

CBS-PIB+ versus CBS-PIB- P <0.05, CBS-PIB+ versus NC P <0.05

left

−2.20 ± 1.38

−1.06 ± 1.56

0.00 ± 1.00

0.000

CBS-PIB+ versus NC P <0.001, CBS-PIB- versus NC P <0.05

LI

13.10 ± 8.20

8.45 ± 6.95

2.00 ± 1.41

0.000

CBS- PIB+ versus NC P <0.005, CBS-PIB- versus NC P <0.021

  1. CBS-PIB+, corticobasal syndrome positive for Pittsburgh compound B; CBS-PIB-, corticobasal syndrome negative for Pittsburgh compound B; FDG, fluorodeoxyglucose; LI, lateralization index; NC, normal control; ROI, region of interest. Data are mean ± standard deviation.