|
Syndromic diagnosis
|
CBS-PIB + (number = 11)
|
CBS-PIB - (number = 14)
|
NC (number = 26)
|
P
|
Post hoc
|
|---|
|
Age at PET
|
66.9 ± 5.5
|
65.8 ± 8.8
|
70.2 ± 2.9
|
0.054
| |
|
Age at MRI
|
67.2 ± 5.2
|
66.1 ± 9.3 (n = 13)
| |
0.110
| |
|
Age at first clinic visit
|
65.6 ± 9.1
|
66.5 ± 5.1
|
n/a
|
0.750
| |
|
Male: Female
|
6:5
|
6:8
|
14:12
|
0.810
| |
|
Education, years
|
15.7 ± 2.2
|
15.8 ± 2.4
|
17.3 ± 2.0
|
0.620
| |
|
MMSE
|
22.9 ± 6.3
|
22.4 ± 6.9
|
29.2 ± 1.2
|
0.0001
|
CBS-PIB+ vs NC P <0.05,
|
|
CBS-PIB- vs NC P <0.01
|
|
CDR
|
0.7 ± 0.5
|
0.9 ± 0.6
|
n/a
|
0.830
| |
|
CDR-SB
|
4.7 ± 3.2
|
3.7 ± 2.6
|
n/a
|
0.400
| |
|
APOE4 (0,1,2)
|
4, 6, 0 (n = 10)
|
9, 1, 0 (n = 10)
|
17, 8, 1
|
0.066
|
CBS-PIB+ vs CBS-PIB- P < 0.05
|
- CBS-PIB+, Corticobasal syndrome positive for Pittsburgh compound B; CBS-PIB-, Corticobasal syndrome negative for Pittsburgh compound B; CDR, Clinical Dementia Rating; CDR-SB, Clinical Dementia Rating sum of boxes; MMSE, Mini-mental State Examination; n/a, not applicable; NC, normal control. Data are mean ± standard deviation.
