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Figure 10 | Alzheimer's Research & Therapy

Figure 10

From: Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson’s disease

Figure 10

Percentage of soluble α-syn phosphorylated at Ser129 after exposure of SH-SY5Y cells to aggregated or soluble Aβ1-42 and Aβ1-40. The percentage of soluble α-syn phosphorylated at Ser129 was much lower than the figure for insoluble α-syn. The percentage tended to fall after exposure to aggregated Aβ1-42 and Aβ1-40, particularly at 10 μM, but not significantly so, and did not change noticeably after exposure to soluble Aβ. The bars show the mean and SE of measurements from five separate experiments. Aβ, amyloid-β.

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