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Table 4 Mean (± SEM) scores on neuropsychological, neuropsychiatric and functional measures in the CBS and VHF-DLB groups

From: Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography

Psychometric measures

CBS (number)

VHF-DLB (number)

General cognition

  

MMSE/30 (number =59)

21.7 ± 1.2 (31)

22.1 ± 1.1 (28)

Clock Drawing Test/10 (number =26)

6.9 ± 0.8 (9)

7.7 ± 0.6 (17)

NART/127.8 (number =38)

107.5 ± 1.9 (19)

108.4 ± 2.1 (19)

Raven’s Progressive Matrices (number =40)

21.9 ± 1.6 (22)

21.2 ± 1.3 (18)

DRS/144 (number =53)

113.5 ± 4.1 (26)

114.6 ± 3.7 (27)

Memory

  

CVLT Long Delay Free Recall/16 (number =46)a

6.6 ± 0.6 (21)

2.4 ± 0.5 (25)

CVLT Long Delay Cued Recall/16 (number =46)a

7.4 ± 0.6 (21)

3.9 ± 0.5 (25)

Delayed Visual Reproduction /41 (number =40b

10.5 ± 2.3 (19)

4.2 ± 1.2 (21)

Language

  

WAB total/100 (number =38)

85.7 ± 2.5 (23)

86.5 ± 2.2 (15)

Boston Naming/30 (number =47)

24.0 ± 1.0 (22)

22.5 ± 1.1 (25)

Semantic Fluency/20 (number =53)

9.8 ± 1.2 (26)

10.3 ± 1.0 (27)

Praxis

  

WAB praxis/60 (n =48)

53.2 ± 1.6 (27)

55.6 ± 0.6 (21)

Attention and working memory

  

Digit span - forward/12 (number =50)

7.0 ± 0.6 (23)

6.8 ± 0.5 (27)

Digit span - backward/12 (number =50)

4.6 ± 0.6 (23)

4.3 ± 0.5 (27)

Visuospatial abilities

  

Rey Osterieth Complex Figure/36 (number =45)

17.0 ± 3.0 (20)

18.5 ± 2.3 (25)

Benton Line Orientation /30 (number =44)

13.2 ± 2.4 (21)

13.4 ± 2.3 (23)

Executive functions

  

Phonemic (FAS) fluency (number =47)

19.1 ± 2.7 (21)

22.1 ± 3.2 (26)

Trail Making Test A (time in seconds) (number =42)

108.7 ± 14.7 (19)

101.4 ± 11.5 (23)

Trail Making Test B (time in seconds) (number =31)

214.5 ± 39.7 (13)

193.6 ± 20.9 (18)

WCST categories/6 (number =44)

(22)

(22)

Categories 0 to 1: Counts (%)

11 (50%)

17 (77%)

Categories 2 to 4: Counts (%)

11 (50%)

5 (23%)

WCST perseverative errors (number =44)

11.7 ± 2.9 (22)

19.8 ± 3.4 (22)

Neuropsychiatric features

  

Cornell Depression (number =54)

22.8 ± 2.6 (30)

16.0 ± 2.7 (24)

Neuropsychiatric Inventory/144 (number =55)

12.1 ± 2.5 (29)

10.5 ± 2.4 (26)

Functional measures

  

DAD (%) (number =57)

68.8 ± 5.7 (30)

78.9 ± 4.1 (27)

  1. aP <0.005; bP <0.05. The number of patients tested is listed next to individual measures. Missing data are secondary to the inability of the patient to complete the test. CBS, corticobasal syndrome; CVLT, California Verbal Learning Test; DAD, Disability Assessment Scale for Dementia; DRS, Mattis Dementia Rating Scale; FAS, F-, A-, and S-phonemic fluency; MMSE, Folstein’s Mini-Mental State Exam; NART, National Adult Reading Test; SEM, standard error of the mean; VHF-DLB, visual hallucination-free dementia with Lewy bodies; WAB, Western Aphasia Battery; WCST, Wisconsin Card Sort Test.
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Alzheimer's Research & Therapy

ISSN: 1758-9193