Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography

Table 3 Clinical characteristics of CBS sample

Clinical characteristics	Frequency (%) at time of investigation (N =31)	Frequency (%) at follow-up (N =31)
Extrapyramidal features
Rigidity (asymmetric)	28 (90.3%)	31 (100%)
Dystonia	16 (51.6%)	18 (58.1%)
Levodopa trial with poor response^a	13 (41.9%)	13 (41.9%)
Tremor – postural/action	8 (25.8%)	11 (35.6%)
Cortical features
Apraxia	28 (90.3%)	31 (100%)
Cortical sensory loss	19 (61.3%)	19 (61.3%)
Alien-limb phenomenon	1 (3.2%)	3 (9.7%)
Limb levitation	7 (22.6%)	10 (32.3%)
Myoclonus	9 (29.0%)	13 (41.9%)
Early dementia	22 (71.0%)	22 (71.0%)
Language disturbance	24 (77.4%)	24 (77.4%)

^aThirteen patients had a trial of levodopa and all responded poorly based on clinical assessment. Average time for emergence of additional symptoms or signs on follow-up was 1.0 ± 0.3 years. CBS, corticobasal syndrome; N, number.

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