Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography

Table 2 Clinical characteristics of patients with VHF-DLB at the time of entry into the study

Clinical characteristics	Frequency (%) at investigation (N =30)	Frequency (%) at follow-up (N =30)
Core features
Parkinsonism	26 (86.7)	30 (100%)^a
Rigidity	24 (80.0)	-
Gait disturbance	21 (70.0)	-
Bradykinesia	20 (66.7)	-
Tremor	17 (56.7)	-
Postural instability	15 (50.0)	-
Hypomimia	15 (50.0)	-
Fluctuating cognition	18 (60.0)	18 (60.0)
Visual hallucinations	0 (0)	0 (0)
Supportive features
REM sleep behaviour disorder	7 (23.3)	7 (23.3)
Neuroleptic sensitivity	3 (10.0)	3 (10.0)^b
Suggestive features
Depressive symptoms	14 (46.7)	14 (46.7)
Systematised delusions	7 (23.3)	7 (23.3)
Orthostatic hypotension	5 (16.7)	5 (16.7)
Non-visual hallucinations	5 (16.7)	5 (16.7)
Syncope	1 (3.3)	1 (3.3)

^aAll patients developed parkinsonism within one year of investigation; ^bneuroleptic use avoided given DLB diagnosis. Only three patients were exposed to an antipsychotic and all had sensitivity. N, number; REM, rapid eye movement; VHF-DLB, visual hallucination-free dementia with Lewy bodies.

ISSN: 1758-9193