Subjects with CUPS
| |
Subgroup: H&Y stage
|
Subgroup: MMSE score
|
Subgroup: age of subjects at baseline
|
Subgroup: clinical syndrome predominance at baselinea
|
---|
1-year clinical diagnosis
|
Ioflupane [123I] imaging results
|
<2
|
≥2
|
Total
|
<29
|
≥29
|
Total
|
<68 years
|
≥68 years
|
Total
|
TD
|
BRP dominant
|
B
|
Total
|
---|
PS
|
Normal
|
2
|
1
|
3
|
1
|
2
|
3
|
2
|
1
|
3
|
0
|
2
|
1
|
3
|
|
Abnormal
|
26
|
20
|
46
|
19
|
27
|
46
|
15
|
31
|
46
|
10
|
17
|
19
|
46
|
Non-PS
|
Normal
|
20
|
21
|
41
|
16
|
25
|
41
|
15
|
26
|
41
|
25
|
4
|
12
|
41
|
|
Abnormal
|
0
|
2
|
2
|
1
|
1
|
2
|
2
|
0
|
2
|
0
|
2
|
0
|
2
|
Total
| |
48
|
44
|
92
|
37
|
55
|
92
|
34
|
58
|
92
|
35
|
25
|
32
|
92
|
- Data presented as numbers. B, balanced; BRP, bradykinesia, rigidity, postural instability; CUPS, clinically uncertain parkinsonian syndrome; H&Y, Hoehn and Yahr; MMSE, Mini-Mental State Examination; PS, parkinsonian syndrome; TD, tremor dominant. aTD, tremor score > BRP; BRP dominant, BRP > tremor score; B, maximal score of BRP = tremor score. Scores for these motor signs were 1 for none, 2 for possible, and 3 for definite.