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Table 3 Hippocampal volume partial correlations with and without including diagnostic category a

From: Association between cell-bound blood amyloid-β(1 - 40) levels and hippocampus volume

  Not including diagnostic category Including diagnostic category
Partial correlation P-value Partial correlation P-value
ln DA Aβ(1 - 40) 0.05 0.64 −0.01 0.92
ln DA Aβ(1 - 42) −0.08 047 −0.15 0.20
ln TP Aβ(1 - 40) 0.03 0.78 0.01 0.92
ln TP Aβ(1 - 42) −0.01 0.37 −0.14 0.22
ln CP Aβ(1 - 40)* −0.37 0.0007 −0.35 0.002
ln CP Aβ(1 - 42) −0.16 0.17 −0.2 0.07
Total Aβ1 −0.18 0.11 −0.24 0.03
ADNI Aβln Aβ(1 - 40) 0.08 0.05 0.1 0.01
ADNI Aβln Aβ(1 - 42) 0.08 0.04 0.09 0.02
  1. aADNI: Alzheimer’s Disease Neuroimaging Initiative; Aβ: Amyloid-β; CP: Cellular pellet; DA: Directly accessible. The data are derived from the AB128 and ADNI data sets and represent partial correlations of Aβ blood levels with left hippocampal volume adjusted for the covariates age, gender, ApoE, education, creatinine levels and phenotype. The left columns show the correlations and P-values if phenotype is excluded as covariate. ADNI Aβln Aβ(1 - 40) and Aβln Aβ(1 - 42) values are placed underneath their comparative quantities. *Bold text highlights the correlation of the Aβln CP Aβ(1 - 40) fraction in the AB128 study.