Figure 5From: Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review Sampling frame for a longitudinal aging cohort. Prospective longitudinal follow-up allows estimation of new incident cases of stroke and Alzheimer's disease (AD). In ideal circumstances, it also allows the collection of a representative autopsy sample.Back to article page