Figure 4

Multi-tracer positron emission tomography concept to study pathological and functional processes in the brain. Multi-positron emission tomography tracer concept applied in drug trials combined with atrophy studies (magnetic resonance imaging (MRI)), cerebrospinal fluid (CSF) biomarkers and cognitive testing. ¹¹C-PMP, acetylcholinesterase; ¹¹C-PIB, amyloid; ¹¹C-deprenyl, astrocytosis; ¹¹C-nicotine, nicotinic receptors; ¹⁸F-FDG, 2-[¹⁸F]-fluoro-2-deoxy-D-glucose metabolism. Red, high activity; yellow, medium activity; blue, low activity.