|
Administration
|
Time (minutes)
|
|---|
| | |
Early stage
|
Middle stage
|
Late stage
|
Overall
|
|---|
|
ROSA
|
BL
|
13.6 (7.27)
|
15.5 (6.72)
|
14.4 (5.50)
|
14.5 (6.82)
|
| |
W12
|
13.2 (5.48)
|
15.3 (6.54)
|
14.3 (4.79)
|
14.3 (5.93)
|
|
ADAS-cog
|
BL
|
24.7 (7.39)
|
25.2 (7.51)
|
-
|
25.2 (7.51)
|
| |
W12
|
22.7 (7.45)
|
25.7 (8.06)
|
-
|
24.3 (7.89)
|
|
SIB
|
BL
|
-
|
24.8 (9.08)
|
29.0 (10.21)
|
26.3 (9.89)
|
| |
W12
|
-
|
24.5 (10.20)
|
26.4 (11.02)
|
25.4 (10.58)
|
|
NPI
|
BL
|
14.3 (6.60)
|
15.9 (11.87)
|
18.2 (7.81)
|
15.6 (9.54)
|
| |
W12
|
13.7 (7.20)
|
13.5 (6.46)
|
17.0 (8.40)
|
14.1 (7.19)
|
|
DAD
|
BL
|
10.8 (6.20)
|
11.5 (5.28)
|
12.4 (5.89)
|
11.4 (5.77)
|
| |
W12
|
9.9 (4.66)
|
11.3 (4.84)
|
11.6 (6.00)
|
10.8 (5.00)
|
- Data presented as mean (standard deviation). ADAS-cog, Alzheimer's Disease Assessment Scale - cognitive subscale; BL, baseline; DAD, Disability Assessment for Dementia; NPI, Neuropsychiatric Inventory; ROSA, Relevant Outcome Scale for Alzheimer's Disease; SIB, Severe Impairment Battery; W12, week 12 after baseline.
