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Table 3 Logistic regression models illustrating the odds of all-cause dementia, Alzheimer's disease and vascular dementia (95% confidence intervals) by untreated and treated vascular conditions and diabetes

From: Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study

  All-cause dementia Alzheimer's disease Vascular dementia
  Basic adjusted models* Fully adjusted models† Basic adjusted models* Fully adjusted models† Basic adjusted models* Fully adjusted models‡
Hypertension       
   Untreated 1.3 (0.6-2.9) 1.3 (0.6-3.0) 1.4 (0.7-2.8) 1.5 (0.7-3.1) 2.6 (0.5-14.3) 2.9 (0.4-19.9)
   Treated 0.6 (0.3-1.0) 0.5 (0.3-1.0) 0.4 (0.2-0.8) 0.5 (0.2-1.0) 1.4 (0.5-4.5) 1.7 (0.5-5.3)
Diabetes       
   Untreated 2.5 (0.7-8.1) 2.3 (0.7-7.2) 2.1 (0.6-7.0) 2.1 (0.6-6.8) 0.8 (0.1-8.6) (Insufficient cases observed)
   Treated 0.7 (0.4-1.5) 0.9 (0.5-1.8) 0.4 (0.1-1.5) 0.5 (0.1-1.6) 0.8 (0.4-1.4) 0.6 (0.3-1.2)
Heart disease       
   Untreated 2.1 (1.4-3.3) 1.8 (1.0-3.3) 1.7 (0.8-3.7) 1.6 (0.5-4.6) 4.2 (0.8-20.8) 4.1 (0.9-18.8)
   Treated 1.3 (0.7-2.5) 1.2 (0.6-2.4) 1.3 (0.6-2.8) 1.5 (0.7-3.1) 1.8 (0.6-5.5) 2.1 (0.7-6.6)
Stroke       
   Untreated 3.8 (2.2-6.6) 3.8 (2.0-7.2) 2.6 (1.6-4.2) 2.4 (1.3-4.2) § §
   Treated 3.2 (1.6-6.4) 3.5 (1.7-7.3) 1.8 (0.9-3.7) 1.9 (0.8-4.2) § §
  1. Population weights are used to adjust for the sampling design. 'Untreated' and 'Treated' categories were defined on the basis of a nurse inspection of medicine bottles currently used. *Adjusted for age, sex, education, ethnicity, and Health and Retirement Study (HRS) wave. †Adjusted for age, sex, education, ethnicity, HRS wave, apolipoprotein ε4 (APOE ε4) status, and all other variables in the table. ‡Adjusted for age, sex, education, ethnicity, HRS wave, APOE ε4 status, and all other variables in the table excluding stroke. §Not examined as stroke is a central diagnostic criterion for vascular dementia [31].