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Figure 4 | Alzheimer's Research & Therapy

Figure 4

From: The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis

Figure 4

Progression of Lewy body pathology. Schematic diagram of the pattern of alpha-synuclein deposition as hypothesised by Braak and colleagues [32]. Deposition is first seen in the peripheral autonomic nervous system, including the enteric nervous system. This is then followed by deposition in the brainstem, ascending to the limbic system and, finally, the neocortex. Illustration from [88], available under creative commons license.

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