Variable | Mean ± SD (n = 247) |
---|---|
Time to death, n = 221 (years) | 6.4 ± 3.0 |
Age (years) | 75.2 ± 6.1 |
Sex (female) | 69% |
MMSE score (0 to 30 points) | 21.3 ± 5.1 |
Temporal horn ratio (medial temporal atrophy) | 0.040 ± 0.017 |
Evans ratio (frontal atrophy) | 0.33 ± 0.038 |
Cella media index (central atrophy) | 0.22 ± 0.040 |
CSF sVCAM-1 (neuroinflammatory pathology, μg/L) | 11.7 ± 4.3 |
ARWMC (cerebrovascular pathology, 0 to 18 points) | 3.2 ± 3.4 |
Albumin ratio (BBB integrity) | 0.0075 ± 0.0032 |
CSF Tau (pg/ml) | 619 ± 322 |
CSF P-tau (pg/ml) | 76 ± 31 |
CSF Aβ42 (pg/ml) | 410 ± 99 |
APOE ϵ4/ϵ4 | 22% |