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Table 1 Characteristics (variables entered into the Cox Regression Analysis)

From: Cerebral inflammation is an underlying mechanism of early death in Alzheimer’s disease: a 13-year cause-specific multivariate mortality study

Variable Mean ± SD (n = 247)
Time to death, n = 221 (years) 6.4 ± 3.0
Age (years) 75.2 ± 6.1
Sex (female) 69%
MMSE score (0 to 30 points) 21.3 ± 5.1
Temporal horn ratio (medial temporal atrophy) 0.040 ± 0.017
Evans ratio (frontal atrophy) 0.33 ± 0.038
Cella media index (central atrophy) 0.22 ± 0.040
CSF sVCAM-1 (neuroinflammatory pathology, μg/L) 11.7 ± 4.3
ARWMC (cerebrovascular pathology, 0 to 18 points) 3.2 ± 3.4
Albumin ratio (BBB integrity) 0.0075 ± 0.0032
CSF Tau (pg/ml) 619 ± 322
CSF P-tau (pg/ml) 76 ± 31
CSF Aβ42 (pg/ml) 410 ± 99
APOE ϵ4/ϵ4 22%
  1. Aβ, beta-amyloid; APOE, apolipoprotein E; ARWMC, Age-Related White Matter Changes scale; BBB, blood–brain barrier; CSF, cerebrospinal fluid; MMSE, the Mini-Mental State Examination; SD, standard deviation; sVCAM-1, soluble vascular cell adhesion molecule-1.