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Figure 4 | Alzheimer's Research & Therapy

Figure 4

From: Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

Figure 4

Comparison of behavior changes in APP/PS1 KI mice with other common Alzheimer's disease mouse models. Data analysis from the literature focused on a compilation of the most widely used behavioral tasks to assess the onset/progression of motor function impairment, anxiety-related behavior, and cognitive impairment. Blue data, the Alzheimer's disease (AD) mouse performed the same as the wild-type (WT) control; yellow data, the AD mouse was increased from control; red data, the AD mouse was decreased from control. The numbers within the data boxes refer to the literature citation. APP/PS1 KI, amyloid precursor protein/presenilin-1 knock-in.

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