Figure 3From: DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's diseaseThe potential link of reduced DNA-dependent protein kinase (DNA-PK), phosphorylation status of replication protein A (RPA) and p53 to neuronal apoptosis, and genomic instability that may lead to Alzheimer's disease (AD). Aβ, amyloid beta; HR, homologous recombination; NHEJ, non-homologous end joining; RNA Pol I, RNA polymerase I; ROS, reactive oxygen species.Back to article page