Figure 2
From: DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease
The potential role of the amyloid beta (Aβ)-induced loss of DNA-dependent protein kinase (DNA-PK)-mediated non-homologous end joining (NHEJ) or homologous recombination (HR) (or both) in the development of Alzheimer's disease (AD). ATM, Ataxia telangiectasia mutated protein; DSB, double-strand break.