Table 1 Demographics and baseline characteristics (intent-to-treat population).
Characteristics | Donepezil 10 mg/day | Donepezil 23 mg/day |
|---|---|---|
Age | Â | Â |
Mean (SD) | 73.8 (8.6) | 73.8 (8.5) |
| Â | (n = 462) | (n = 909) |
Gender | Â | Â |
Male, n (%) | 175 (37.9) | 335 (36.9) |
Female, n (%) | 287 (62.1) | 574 (63.1) |
Total patients, n | 462 | 909 |
ADCS-ADL-sev | Â | Â |
Mean (SD) | 34.5 (11.2) | 34.1 (10.9) |
| Â | (n = 461) | (n = 908) |
CIBIS-plus Mean (SD) | 4.38 (0.89) | 4.42 (0.85) |
| Â | (n = 461) | (n = 904) |
MMSE | Â | Â |
Mean (SD) | 13.1 (4.7) | 13.1 (4.99) |
| Â | (n = 462) | (n = 908) |
SIB | Â | Â |
Mean (SD) | 75.6 (16.3) | 74.2 (17.6) |
| Â | (n = 462) | (n = 907) |
Individual SIB domain scores, mean (SD): | Â | Â |
Language | 36.7 (8.40) | 36.2 (9.02) |
Memory | 8.5 (3.03) | 8.2 (3.24) |
Praxis | 5.5 (2.33) | 5.4 (2.45) |
Visuospatial ability | 6.5 (2.04) | 6.3 (2.34) |
Attention | 4.3 (1.65) | 4.2 (1.66) |
Orientation | 3.7 (1.45) | 3.7 (1.45) |
Social | 5.3 (1.14) | 5.3 (1.06) |
Construction | 3.4 (1.16) | 3.3 (1.25) |
Orienting to name | 1.7 (0.59) | 1.6 (0.60) |
Total patients, n | 462 | 907 |