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Table 2 Final linear regression models of Lp-PLA2 activity by diagnosis group

From: Plasma lipoprotein-associated phospholipase A2 activity in Alzheimer's disease, amnestic mild cognitive impairment, and cognitively healthy elderly subjects: a cross-sectional study

  Model Without LDL Model With LDL
  β (SE)† P β (SE)† P
AD (versus Control)* 7.7 (7.2) 0.29 8.3 (5.7) 0.15
aMCI (versus Control)* 11.3 (7.2) 0.12 11.6 (5.8) 0.05
Age (1 year increase)* -0.19 (0.3) 0.58 0.39 (0.3) 0.16
Statin use (yes versus no)* -23.9 (7.0) 0.001 -11.2 (5.8) 0.06
Gender (female versus male)* -10.6 (6.2) 0.09 -23.8 (4.9) < .0001
LDL (1 mmol/l increase) NA NA 24.1 (2.5) < .0001
BMI 1.8 (0.8) 0.03 0.4 (0.69) 0.55
Diabetes Type 2 (yes versus no) -23.3 (14.0) 0.10 -2.7 (11.6) 0.81
  1. Final models selected through backwards elimination. Covariates with P- value < 0.05 are presented in bold. *Forced to remain in the model. † β estimates correspond to the expected difference in mean Lp-PLA2 activity relative to comparator for binary variables or per one unit increase in continuous covariates.