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Table 3 Subcortical volumes in C9ORF72 mutation and healthy control groups

From: Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions

  

C9ORF72

Control

 
  

% per year

Atrophy (ml/year)

SD

% per year

Atrophy (ml/year)

SD

P value

Thalamus

Right

3.4

0.16

0.17

-0.2

-0.02

0.08

0.006

 

Left

2.5

0.23

0.29

-0.3

-0.02

0.09

0.03

Globus pallidus

Right

1.7

0.05

0.10

0.0

0.00

0.03

n/s

 

Left

2.9

0.03

0.14

-1.1

-0.02

0.06

0.04

Caudate

Right

-2.6

-0.09

0.15

0.3

0.01

0.06

n/s

 

Left

0.7

0.02

0.07

0.0

0.00

0.13

n/s

Amygdala

Right

-2.8

-0.04

0.08

0.1

0.00

0.04

n/s

 

Left

2.1

0.03

0.06

0.6

0.01

0.06

n/s

Hippocampus

Right

1.7

0.07

0.08

1.0

0.04

0.06

n/s

 

Left

1.4

0.05

0.03

0.6

0.03

0.09

n/s

Putamen

Right

-0.6

-0.03

0.10

0.0

0.00

0.06

n/s

 

Left

-1.2

-0.06

0.13

-0.1

0.00

0.10

n/s

  1. Mean annualised rates of change are expressed as a percentage (%) and as the millilitre (ml) change from baseline. C9ORF72, chromosome 9 open reading frame 72; n/s, not significant p < 0.05; SD, standard deviation.