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Figure 3 | Alzheimer's Research & Therapy

Figure 3

From: Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort

Figure 3

Enzyme-linked immunosorbent assays comparing GRN plasma levels between GRN mutation carriers and controls. Measurement of GRN plasma levels for a known GRN mutation (left) and the novel GRN mutation (right), Ile256IlefsX27, observed in our study compared with Alzheimer's disease cases and non-demented older controls. GRN, progranulin; mut, mutant; wt, wild-type.

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Alzheimer's Research & Therapy

ISSN: 1758-9193