Fig. 3

Comparisons of plasma biomarkers and neuroimaging between different clinical groups. Comparisons of (A) plasma Aβ₄₂/Aβ₄₀, (B) plasma p-Tau₁₈₁, (C) plasma GFAP, (D) plasma NfL, (E) Aβ PET, (F) tau PET, (G) hippocampal volume and (H) temporal-MetaROI cortical thickness between NC, SCD, MCI, and dementia groups. Plasma p-Tau₁₈₁, plasma GFAP, and plasma NfL were log₁₀ transferred. The mean intra-assay and inter-assay coefficient of variation (CV)s were respectively 12% and 17% for plasma Aβ₄₂, 9% and 17% for plasma Aβ₄₀, 7% and 9% for plasma NfL, 5% and 14% for plasma GFAP, and 10% and 13% for plasma p-Tau₁₈₁