Fig. 3
From: Impact of amyloid and tau positivity on longitudinal brain atrophy in cognitively normal individuals
Mean measurement trajectories and 95% confidence bands using LOESS for each group classified by amyloid and tau positivity/negativity. Abbreviations: A −  = amyloid negative; A +  = amyloid positive; LOESS = locally estimated scatterplot smoothing; PACC = Preclinical Alzheimer Cognitive Composite; T −  = tau negative; T +  = tau positive