Fig. 5
From: Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
Cerebral capillary red blood cell flux (RBC flux) at day 0 (no LPS injection), day 7 and day 14 (with LPS injection) in WT and AD brain. (A) Histograms showing RBC flux in all measured capillary points in cortical layers II to IV. (B-C) Mean RBC flux and coefficient of variation over all measured mice in both cohorts over the course of LPS-induced inflammation. Each bar represents mean ± standard error over all measured mice in each cohort. Connected scatterplot shows the RBC flux and the CV of each individual mouse. D-E Diameter of penetrating arteriole and venule in WT and AD mice on day 0, day 7 and day 14