Variables | Early-onset dementia (n = 2,368) | Late-onset dementia (n = 32,893) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Death (n) | % | Non-death (n) | % | p value | Death (n) | % | Non-death (n) | % | p value | |
Total Participants | 442 | 18.7 | 1,926 | 81.3 | Â | 12,969 | 39.4 | 19,924 | 60.6 | Â |
Age |  |  |  |  | < 0.001 |  |  |  |  | < 0.001 |
 Mean ± Standard deviation | 54.8 ± 5.2 | 52.6 ± 5.1 |  | 77.2 ± 6.8 | 72.1 ± 5.76 |  | ||||
Sex |  |  |  |  | < 0.001 |  |  |  |  | < 0.001 |
 Male | 310 | 70.1 | 926 | 48.1 |  | 5,087 | 39.2 | 5,638 | 28.3 |  |
 Female | 132 | 29.9 | 1,000 | 51.9 |  | 7,882 | 60.8 | 14,286 | 71.7 |  |
Risk factors of interest | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Hypertension | 224 | 50.7 | 833 | 43.3 | 0.005 | 9,782 | 75.4 | 14,119 | 70.9 | < 0.001 |
 Diabetes mellitus | 205 | 46.4 | 705 | 36.6 | < 0.001 | 6,832 | 52.7 | 10,311 | 51.8 | 0.100 |
 Atrial fibrillation | 16 | 3.6 | 38 | 2.0 | 0.037 | 752 | 5.8 | 812 | 4.1 | < 0.001 |
 Hyperlipidemia | 179 | 40.5 | 810 | 42.1 | 0.549 | 5,991 | 46.2 | 10,765 | 54.0 | < 0.001 |
 Osteoporosis | 54 | 12.2 | 363 | 18.8 | 0.001 | 5,806 | 44.8 | 9,883 | 49.6 | < 0.001 |
Other risk factors in the Charlson comorbidity index | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Myocardial infarct | 59 | 13.3 | 139 | 7.2 | < 0.001 | 2,293 | 17.7 | 3,026 | 15.2 | < 0.001 |
 Congestive heart failure | 31 | 7.0 | 62 | 3.2 | < 0.001 | 1,785 | 13.8 | 1,898 | 9.5 | < 0.001 |
 Peripheral vascular disease | 105 | 23.8 | 452 | 23.5 | 0.898 | 5,407 | 41.7 | 8,425 | 42.3 | 0.286 |
 Cerebrovascular disease | 110 | 24.9 | 389 | 20.2 | 0.029 | 4,083 | 31.5 | 5,602 | 28.1 | < 0.001 |
 Chronic pulmonary disease | 166 | 37.6 | 767 | 39.8 | 0.379 | 7,716 | 59.5 | 11,751 | 59.0 | 0.352 |
 Rheumatic or connective tissue disease | 10 | 2.3 | 30 | 1.6 | 0.300 | 346 | 2.7 | 579 | 2.9 | 0.202 |
 Gastric or peptic ulcer | 178 | 40.3 | 822 | 42.7 | 0.355 | 6,494 | 50.1 | 11,229 | 56.4 | < 0.001 |
 Mild liver disease | 254 | 57.5 | 1,100 | 57.1 | 0.892 | 6,713 | 51.8 | 11,534 | 57.9 | < 0.001 |
 Hemiplegia or paraplegia | 45 | 10.2 | 107 | 5.6 | < 0.001 | 634 | 4.9 | 699 | 3.5 | < 0.001 |
 Moderate or severe renal disease | 28 | 6.3 | 44 | 2.3 | < 0.001 | 628 | 4.8 | 608 | 3.1 | < 0.001 |
Socioeconomic status | Â | Â | Â | Â | 0.348 | Â | Â | Â | Â | 0.848 |
 Upper 20% | 68 | 15.4 | 332 | 17.2 |  | 4,265 | 32.9 | 6,532 | 32.8 |  |
 Lower 80% | 374 | 84.6 | 1,594 | 82.8 |  | 8,704 | 67.1 | 13,392 | 67.2 |  |
Residential area | Â | Â | Â | Â | 0.975 | Â | Â | Â | Â | 0.618 |
 Urban | 189 | 42.8 | 822 | 42.7 |  | 4,828 | 37.2 | 7,363 | 37.0 |  |
 Rural | 253 | 57.2 | 1,104 | 57.3 |  | 8,141 | 62.8 | 12,561 | 63.0 |  |