| UPDRS |
---|
| β | P |
---|
AD spectrum | | |
Left amygdala | 0.181 | 0.001 |
Right amygdala | 0.187 | 0.001 |
Left hippocampus | 0.148 | 0.010 |
Right hippocampus | 0.130 | 0.023 |
Left entorhinal cortex | 0.123 | 0.036 |
Right entorhinal cortex | 0.158 | 0.006 |
DLB spectrum | | |
Left amygdala | 0.216 | < 0.001 |
Right amygdala | 0.227 | < 0.001 |
Left hippocampus | 0.162 | 0.004 |
Right hippocampus | 0.146 | 0.009 |
Left entorhinal cortex | 0.131 | 0.022 |
Right entorhinal cortex | 0.178 | 0.002 |
Disease group | | |
Left amygdala | 0.191 | < 0.001 |
Right amygdala | 0.174 | 0.001 |
Left hippocampus | 0.179 | < 0.001 |
Right hippocampus | 0.155 | 0.002 |
Left entorhinal cortex | 0.163 | 0.002 |
Right entorhinal cortex | 0.161 | 0.002 |
- The data are the results of univariable general linear models for the UPDRS motor score using MTL metabolism as a predictor after controlling for age, sex, and education. Significant P-values are shown in boldface after false discovery rate correction for multiple statistical tests across the six MTL regions. Analyses were performed separately on the AD spectrum (NC + AD + MD), DLB spectrum (NC + DLB + MD), and in the disease group (AD + DLB + MD). β = standardized beta coefficient. Abbreviations: AD, Alzheimer’s disease; DLB, dementia with Lewy bodies; MD, mixed disease; MTL, medial temporal lobe; NC, normal control; UPDRS, Unified Parkinson’s Disease Rating Scale