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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Comparing a pre-defined versus deep learning approach for extracting brain atrophy patterns to predict cognitive decline due to Alzheimer’s disease in patients with mild cognitive symptoms

Fig. 3

ROC curves and AUC for progression to AD dementia. Models using a) clinical data (age, sex, and education, baseline cognition [MMSE score, ADAS delayed word recall] and APOE genotype), b) clinical data, intracranial volume and hippocampal volume, c) clinical data, intracranial volume and FreeSurfer, d) clinical data, MRI and JD. The blue curve shows the results on the BioFINDER test data and the red curves the results on the ADNI data. The solid line presents the mean from the five test folds and ten cross-validation folds, the transparent lines present the induvial results, and the shaded areas show the mean plus/minus one standard deviation

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