Table 1 Demographic and clinical characteristics of included multi-site participants

Gender (M/F)

58

/81

138 /106^a

69

/63

176 /264

127 /105^a

58

/32^b

71

/77

50

/71^a

15

/23^b

101

/140

22

/24

7

/11

40

/31

38

/47

36

/21^b

31

/35

28

/34

19

/23

Age

(mean ± SD)

75.4 ± 6.1

73.0 ± 8.1

74.5 ± 7.2

71.0 ± 6.3

76.0 ± 8.3^a

77.4 ± 7.9^b

64.0 ± 12.5

69.0 ± 9.8^a

73.0 ± 8.8^b

66.2 ± 5.2

68.3 ± 9.6^a

70.4 ± 11.3^b

71.0 ± 8.0

71.6 ± 8.1

73.7 ± 8.3

68.0 ± 6.7

73.1 ± 6.1^a

74.4 ± 8.8^b

Edu

(mean ± SD)

16.7 ± 2.1

16.1 ± 2.6^a

15.6 ± 2.8^b

16.3 ± 2.1

15.7 ± 2.8^a

15.6 ± 2.6^b

12.0 ± 8.3

10.0 ± 4.5^a

9.0 ± 5.0^b

12.4 ± 3.2

11.5 ± 4.2

13.8 ± 2.9

12.0 ± 3.7

10.9 ± 4.3^a

8.3 ± 5.4^b

12.4 ± 3.4

9.0 ± 4.0^a

8.7 ± 5.3^b

sMCI

/pMCI (conversion time)

-

164/80 (21.0 ± 12.0)

-

-

214/17 (21.4 ± 6.3)

-

-

63/58 (22.0 ± 15.0)

-

-

35/11 (17.3 ± 4.3)

-

-

-

-

-

-

-

APOEε4

(-/ +)

83

/56

147

/97^a

16

/116^b

261

/142

136

/78

36

/44^b

67

/28

51

/57^a

18

/13

193

/47

25

/19^a

8

/9^b

-

-

-

-

-

-

Aβ

(-/ +)

31

/13

34/

42^a

4/

39^b

191

/60

57

/32^a

7

/40^b

23

/0

0

/1

0

/4

70

/13

4

/5

2

/2

-

-

-

-

-

-

MMSE

(mean ± SD)

29.0 ± 1.4

27.8 ± 2.0^a

22.0 ± 3.6^b

28.9 ± 1.6

27.6 ± 2.0^a

21.4 ± 4.2^b

28.0 ± 2.1

24.0 ± 3.6^a

18.0 ± 3.8^b

28.8 ± 1.3

25.6 ± 2.9^a

16.8 ± 71^b

27.0 ± 2.2

23.8 ± 3.3^a

14.7 ± 6.2^b

27.2 ± 2.1

23.9 ± 2.8^a

15.1 ± 5.3^b

CDR-SB (mean ± SD)

0.1 ± 0.2

1.5 ± 1.1^a

4.9 ± 1.9^b

0.08 ± 0.3

1.5 ± 1.1^a

6.0 ± 3.0^b

-

-

-

-

-

-

-

-

-

-

-

-