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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: A novel spatiotemporal graph convolutional network framework for functional connectivity biomarkers identification of Alzheimer’s disease

Fig. 1

Comprehensive workflow of the study. a Data collection from three centers: ADNI, Xuanwu Hospital, and Tongji Hospital. b fMRI preprocessing flow. c Graph representation construction based on fMRI. d Architecture of the STGC-GCAM model. e Visualization of imaging biomarkers using BrainNet Viewer. f Correlation analysis between topological features of disease-related brain regions and clinical indicators. g Survival analysis of MCI patients using imaging markers. h Investigation of the mediating effects of brain region topology characteristics on cognitive disorders caused by Aβ, tau, and neural variants

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