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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Deciphering the effect of phytosterols on Alzheimer’s disease and Parkinson’s disease: the mediating role of lipid profiles

Fig. 4

Effects of circulating stigmasterol and sitosterol levels on the risk of Alzheimer’s disease in multivariable Mendelian randomization. The causal effect of circulating stigmasterol (A) and sitosterol (B) on AD disappeared after adjustment of blood lipids in MVMR analysis. AD, Alzheimer’s disease; HDL-C, high-density lipoprotein cholesterol; TG, triglycerides; OR, odds ratio; MVMR, multivariable Mendelian randomization; UKB, UK Biobank; IGAP, International Genomics of Alzheimer’s Project

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Alzheimer's Research & Therapy

ISSN: 1758-9193