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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Deciphering the effect of phytosterols on Alzheimer’s disease and Parkinson’s disease: the mediating role of lipid profiles

Fig. 3

Scatter plots for the causal effect of circulating stigmasterol and sitosterol levels and Alzheimer’s disease. A and B showed the SNPs’ effect on circulating stigmasterol levels and AD using summary-level data from IGAP and IGAP + UKB, respectively. C and D showed the SNPs’ effect on circulating sitosterol levels and AD using summary-level data from IGAP and IGAP + UKB, respectively. The slope indicated the causal estimates for each method. AD, Alzheimer’s disease; MR, Mendelian randomization; SNP, single nucleotide polymorphism; UKB, UK Biobank; IGAP, International Genomics of Alzheimer’s Project

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Alzheimer's Research & Therapy

ISSN: 1758-9193