Vascular dysfunction in sporadic bvFTD: white matter hyperintensity and peripheral vascular biomarkers

Table 3 Partial correlation analysis between MMP-1 and brain metabolism in bvFTD

Vascular factor	Brain regions	R	p	FDR-adjust p
MMP-1	Right inferior frontal	-0.4452	0.0107	0.0168^*
	Right inferior frontal orbital	-0.3864	0.0289	0.0421^*
	Right insula	-0.4332	0.0133	0.0205^*
	Left middle cingulate	-0.4402	0.0117	0.0182^*
	Right middle cingulate	-0.4538	0.0091	0.0144^*
	Left cingulate	-0.4879	0.0046	0.0078^*
	Right cingulate	-0.5160	0.0025	0.0044^*
	Left hippocampus	-0.3842	0.0299	0.0433^*
	Right hippocampus	-0.4561	0.0087	0.0139^*
	Left para-hippocampus	-0.4060	0.0211	0.0315^*
	Right para-hippocampus	-0.4484	0.0101	0.0159^*
	Left amygdala	-0.4396	0.0118	0.0184^*
	Right amygdala	-0.5036	0.0033	0.0057^*
	Right caudate	-0.4003	0.0232	0.0343^*
	Right thalamus	-0.4802	0.0054	0.0090^*
	Right superior temporal	-0.4644	0.0074	0.0120^*
	Right middle temporal	-0.4574	0.0085	0.0136^*
	Right superior frontal	-0.3636	0.0408	0.0576
	Right inferior frontal opercular part	-0.3705	0.0369	0.0525

ISSN: 1758-9193