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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Association between brain amyloid deposition and longitudinal changes of white matter hyperintensities

Fig. 3

Moderating effect of sex on association between Aβ and WMH volume. A, Effect of sex on association between baseline Aβ and change of WMH volume for 2 years. Partial regression plot adjusted for age, APOE ε4 positivity, Vascular risk score, CDR sum of box and baseline WMH. Values in a box indicate coefficient and p-value of interaction term between baseline Aβ and sex. B, Relation between Aβ and change of WMH for 2 years in male. Partial regression plot consisted of change of WMH for 2 years as dependent variable, and baseline Aβ as independent variable, adjusted for age, APOE ε4 positivity, Vascular risk score, CDR sum of box and baseline WMH. C, Relation between Aβ and change of WMH for 2 years in female. Partial regression plot consisted of change of WMH for 2 years as dependent variable, and baseline Aβ as independent variable, adjusted for age, APOE ε4 positivity, Vascular risk score, CDR sum of box and baseline WMH.

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