Skip to main content
Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Characterization of preclinical Alzheimer’s disease model: spontaneous type 2 diabetic cynomolgus monkeys with systemic pro-inflammation, positive biomarkers and developing AD-like pathology

Fig. 6

The synaptic damage in the brain of T2DM monkeys. A-B Synaptophysin (SYP) staining (green) of the FC (A) and EC (B) in the T2DM group and NC group. C-D PSD95 staining (green) of the FC (C) and EC (D) in the T2DM group and NC group. E-F Quantification of number and mean intensity of SYP in FC (E) and EC (F)of the T2DM group and NC group. G-H Quantification of number and mean intensity of PSD95 in FC (G) and EC (H) of the T2DM group and NC group. Results presented as mean ± SD. Unpaired t-test were applied (n = 9/T2DM group; n = 3/NC group) (p > 0.05 = ns; p ≤ 0.05 = *; p ≤ 0.01 = **; p ≤ 0.001 = ***). Scale bars represent 50 μm

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193