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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Characterization of preclinical Alzheimer’s disease model: spontaneous type 2 diabetic cynomolgus monkeys with systemic pro-inflammation, positive biomarkers and developing AD-like pathology

Fig. 2

Levels of AD pathological biomarkers in T2DM monkeys. A, G The levels of plasma (A) and CSF (G) Aβ40 of the T2DM group and NC group. B, H The levels of plasma (B) and CSF (H)Aβ42 of the T2DM group and NC group. C, I The levels of plasma (C) and CSF (I) Aβ 42/40 ratio of the T2DM group and NC group. D, J The levels of plasma (D) and CSF (J) p-tau 181 of the T2DM group and NC group. E, K The levels of plasma (E) and CSF (K) neurofilament protein light chain (NfL) of the T2DM group and NC group. F, L The levels of plasma (F) and CSF (L) GFAP of the T2DM group and NC group. Results presented as mean ± SD. Unpaired t-test were applied (n = 9/T2DM group; n = 9/NC group) (p > 0.05 = ns; p ≤ 0.05 = *; p ≤ 0.01 = **; p ≤ 0.001 = ***)

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Alzheimer's Research & Therapy

ISSN: 1758-9193