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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Characterization of preclinical Alzheimer’s disease model: spontaneous type 2 diabetic cynomolgus monkeys with systemic pro-inflammation, positive biomarkers and developing AD-like pathology

Fig. 1

The expression levels of three inflammatory factors in T2DM monkeys. (A) The levels of serum IL-1β of the T2DM group and NC group. (B) The levels of serum IL-6 of the T2DM group and NC group. (C) The levels of serum TNF-α of the T2DM group and NC group. (D, G) The expression levels of IL-1β in the brain of T2DM group and NC group. (E, H) The expression levels of IL-6 in the brain of T2DM group and NC group. (F, I) The expression levels of TNF-α in the brain of T2DM group and NC group. Results presented as mean ± SD. Unpaired t-test was applied (n = 9/T2DM group; n = 9/NC group) (p > 0.05 = ns; p ≤ 0.05 = *; p ≤ 0.01 = **; p ≤ 0.001 = ***). Scale bars: 50 μm (n = 6/T2DM group; n = 3/NC group)

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Alzheimer's Research & Therapy

ISSN: 1758-9193