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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: The use of synaptic biomarkers in cerebrospinal fluid to differentiate behavioral variant of frontotemporal dementia from primary psychiatric disorders and Alzheimer’s disease

Fig. 1

Concentrations of candidate CSF biomarkers across the diagnostic groups. Analysis of covariance (ANCOVA) models corrected for age, sex, and psychotropic medication use with post hoc pairwise comparisons were used to determine the log10 transformed biomarker differences between the clinical groups, with Bonferroni’s multiple comparison correction. A SNAP25. B Ng. C NPTX2. D GluR4. E NfL. SNAP25, synaptosomal-associated protein 25; Ng, neurogranin; NPTX2, neuronal pentraxin 2; GluR4, glutamate receptor 4; NfL, neurofilament light. bvFTD, behavioral frontotemporal dementia; PPD, primary psychiatric disorders; AD, Alzheimer’s disease. *p < 0.05, **p < 0.01, ***p < 0.001

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