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Table 1 Demographic and clinical characteristics of the study cohort

From: Macular vessel density in the superficial plexus is not a proxy of cerebrovascular damage in non-demented individuals: data from the NORFACE cohort

Variables

Whole cohort (n = 188)

SCD (n = 89)

MCI (n = 99)

Significance

Age (year)

66.30 ± 7.32

68.47 ± 7.27

64.35 ± 6.82

 < 0.001* a

Sex (females)

119 (63.30%)

59 (66.29%)

60 (60.61%)

0.512 b

Education (year)

13.97 ± 4.98

15.71 ± 4.24

12.41 ± 5.11

 < 0.001* a

APOE ε4 status

58 (30.85%)

23 (25.84%)

35 (35.35%)

0.211 b

MMSE score

28.46 ± 1.54

29.07 ± 1.15

27.91 ± 1.64

 < 0.001* a

Hypertension

63 (33.51%)

33 (37.08%)

30 (30.30%)

0.408 b

Diabetes mellitus

11 (5.85%)

4 (4.94%)

7 (7.07%)

0.660 b

Dyslipidemia

76 (40.43%)

39 (43.82%)

37 (37.37%)

0.453 b

Heart disease

19 (10.11%)

10 (11.24%)

9 (9.09%)

0.807 b

Respiratory disease

21 (11.17%)

15 (16.85%)

6 (6.06%)

0.035* b

Stroke

3 (1.60%)

0 (0.00%)

3 (3.03%)

0.258 b

Smoking

69 (36.70%)

20 (22.47%)

49 (49.49%)

 < 0.001* b

  1. Data are shown as mean ± standard deviation for quantitative variables and n (%) for qualitative variables
  2. Abbreviations: APOE Apolipoprotein E, MCI Mild cognitive impairment, MMSE Mini-Mental State Examination, SCD Subjective cognitive decline
  3. *Significance was set up at p < 0.05
  4. aStudent’s t test; bPearson’s chi-square test