Fig. 4

The interaction analysis between age and eGFR. a The interaction analysis among age and eGFR. Scatter plots demonstrated whether age modulated the association between plasma biomarkers and eGFR. The green and blue areas represented the 95% confidence interval. b The association between eGFR and plasma NfL in different eGFR groups. The pink and grey areas represented the 95% confidence interval. All the models above were adjusted for age, sex, education, BMI, APOE genotype, hypertension, diabetes, and stroke. Abbreviations: NfL, neurofilament light chain; eGFR, estimated glomerular filtration rate