Table 5 Annual transition probabilities among unimpaired cognition and AD stages
AD stage | Annual transition probability (%) | ||||||
|---|---|---|---|---|---|---|---|
Unimpaired cognition | MCI due to AD | Mild AD dementia | Moderate AD dementia | Severe AD dementia | Death | Cumulative probabilities of transition to any later stages | |
Unimpaired cognition | 95.8% | 3.2% | 0.4% | 0.1% | 0.0% | 0.5% | 4.2% |
MCI due to AD | 4.8% | 69.5% | 20.1% | 4.3% | 0.7% | 0.7% | 25.8% |
Mild AD dementia | 0.1% | 4.5% | 61.3% | 26.6% | 6.7% | 0.8% | 34.1% |
Moderate AD dementia | 0.0% | 0.1% | 3.9% | 59.6% | 31.1% | 5.3% | 36.4% |
Severe AD dementia | 0.0% | 0.0% | 0.1% | 2.0% | 72.6% | 25.3% | 25.3% |
Death | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 100.0% | - |