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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Genome-wide association study and polygenic risk scores of retinal thickness across the cognitive continuum: data from the NORFACE cohort

Fig. 3

Polygenic risk scores (AD PRS, RNFL PRS, and GCIPL PRS). A Pearson’s correlation coefficient between PRSs (GR@ACE). B Adjusted regression models for RNFL PRS as predictor of dementia (GR@ACE). C Adjusted regression models for GCIPL PRS as predictor of dementia (GR@ACE). D Adjusted regression models for RNFL PRS, GCIPL PRS, and AD PRS as predictors of retinal thickness (meta-analysis Maestro and Triton) and dementia (GR@ACE); beta regression coefficients and log10p values are shown. OI: left eye; OD: right eye

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