Fig. 2

Associations between CSF amyloid and phosphorylated Tau with corresponding plasma concentrations in the exploratory cohort. A CSF and plasma Aβ42/Aβ40 ratio. B CSF and plasma p-Tau181 concentrations. C CSF and plasma p-Tau181/Aβ42 ratio. Graphs are presented with a logarithmic transformed axis, except for the ratios. Data displays individual values with mean regression and 95% prediction lines, with shapes corresponding to the cognitive stage (• NC, ▴ MCI, and ■ AD). Spearman correlation coefficients and p-values are presented for each graph. Abbreviations: Aβ, amyloid beta; AD, Alzheimer’s disease dementia; CSF, cerebrospinal fluid; MCI, mild cognitive impairment; NC, neurological control; p-Tau181, phosphorylated tau protein in the position 181