Table 1 Demographic features of participants included in the current study
A4 (elevated amyloid) | LEARN (non-elevated amyloid) | Total | Test statistic | |
|---|---|---|---|---|
n | 1250 | 541 | 1791 | –– |
Sex/gender | ||||
Women, n (%) | 735 (58.5%) | 331 (61.2%) | 1066 (59.5%) | χ2 = 0.79 p = 0.37 |
Age | ||||
Mean (SD), years | 72.0 (4.85) | 70.5 (4.30) | 71.6 (4.74) | t = 6.63 p < 0.001 |
Ethnicity | ||||
Hispanic or Latinx, n (%) | 36 (2.9%) | 18 (3.3%) | 54 (3.0%) | χ2 = 0.45 p = 0.79 |
Not Hispanic or Latinx, n (%) | 1202 (96.2%) | 519 (95.9%) | 1721 (96.1%) | |
Unknown, n (%) | 12 (1.0%) | 4 (0.7%) | 16 (0.9%) | |
Race | ||||
American Indian or Alaskan Native, n (%) | 2 (0.2%) | 5 (0.9%) | 7 (0.4%) | χ2 = 5.75 p = 0.21 |
Asian, n (%) | 27 (2.2%) | 12 (2.2%) | 39 (2.2%) | |
Black or African American, n (%) | 32 (2.6%) | 14 (2.6%) | 46 (2.6%) | |
White, n (%) | 1173 (93.8%) | 504 (93.2%) | 1677 (93.6%) | |
Unknown, n (%) | 16 (1.3%) | 6 (1.1%) | 22 (1.2%) | |
Education | ||||
Mean (SD), years | 16.6 (2.81) | 16.8 (2.63) | 16.6 (2.76 | t = 1.64 p = 0.10 |
WMH volume | ||||
Total, mean (SD), cm3 | 12.27 (9.47) | 11.91 (9.05) | 12.16 (9.35) | t = 0.78 p = 0.43 |
Frontal lobe, mean (SD), cm3 | 4.76 (4.92) | 4.47 (4.52) | 4.67 (4.81) | t = 1.23 p = 0.21 |
Temporal lobe, mean (SD), cm3 | 1.25 (1.17) | 1.38 (1.21) | 1.29 (1.18) | t = 2.00 p = 0.04 |
Parietal lobe, mean (SD), cm3 | 2.67 (3.11) | 2.53 (2.91) | 2.63 (3.05) | t = 0.93 p = 0.35 |
Occipital lobe, mean (SD), cm3 | 2.29 (1.48) | 2.14 (1.48) | 2.25 (1.48) | t = 2.01 p = 0.04 |