Skip to main content

Table 3 ROC analysis of plasma p-tau 217 for identifying abnormal CSF Aβ42/Aβ40 status

From: Effects of certain pre-analytical factors on the performance of plasma phospho-tau217

Plasma p-tau217

AUC (95% CI)

Sensitivity %

Specificity %

Cut-off

Youden’s Index

Cond 1: thaw at RT, NC

0.845 (0.769, 0.921)

88

72

0.282

.600

Cond 2: thaw at RT, C

0.872 (0.799, 0.945)

80

90

0.247

.700

Cond 3: thaw on ice, NC

0.884 (0.818, 0.951)

86

82

0.252

.680

Cond 4: thaw on ice, C

0.883 (0.813, 0.953)

76

92

0.256

.680

  1. Abbreviations: Aβ+ Amyloid-β positive, Aβ− Amyloid-β negative, AUC Area under the curve, CI Confidence interval, CSF Cerebrospinal fluid, C Centrifugation, Cond Condition, NC Non-centrifugation, ROC Receiver operating characteristic, RT Room temperature
Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193