Diet patterns and cognitive performance in a UK Female Twin Registry (TwinsUK)

Table 3 10-year change in cognitive scores and relative abundance of taxa at follow-up in female twins (n = 131)

Cognitive scores	Taxa	n =	β (95% CI)	q =
Age-related cognition	Dorea	109	− 0.02 (− 0.18, 0.13)	0.75
	Ruminococcaceae UCG-010	109	0.22 (0.06, 0.39)	0.16
	Oxalobacter	109	− 2.26 (− 7.22, 2.69)	0.50
Change in SRT (ms)	Dorea	123	11.19 (− 0.50, 22.89)	0.31
	Ruminococcaceae UCG-010	123	− 7.47 (− 21.83, 6.88)	0.50
	Oxalobacter	123	− 255 (− 575, 64.0)	0.37
Change in SWM (total errors)	Dorea	131	1.20 (− 1.41, 3.81)	0.50
	Ruminococcaceae UCG-010	131	− 3.50 (− 6.43, − 0.57)	0.21
	Oxalobacter	131	− 13.1 (− 78.8, 52.6)	0.73
Change in PAL (total errors)	Dorea	131	1.94 (− 0.76, 4.63)	0.37
	Ruminococcaceae UCG-010	131	− 0.91 (− 3.44, 1.62)	0.59
	Oxalobacter	131	17.8 (− 22.6, 58.3)	0.50
Change in PRM (total correct)	Dorea	131	0.24 (− 0.10, 0.58)	0.37
	Ruminococcaceae UCG-010	131	− 0.45 (− 0.86, − 0.03)	0.25
	Oxalobacter	131	− 2.92 (− 13.3, 7.5)	0.64
Change in DMS (total correct)	Dorea	131	− 0.28 (− 0.77, 0.22)	0.50
	Ruminococcaceae UCG-010	131	0.39 (− 0.18, 0.97)	0.37
	Oxalobacter	131	6.39 (− 6.9, 19.7)	0.50
Change in SSP (span)	Dorea	131	− 0.21 (− 0.45, 0.02)	0.31
	Ruminococcaceae UCG-010	131	0.19 (− 0.06, 0.45)	0.37
	Oxalobacter	131	1.89 (− 4.70, 8.49)	0.64

Values are beta coefficients (95% CI). Model adjusted for age, SES, educational attainment, energy intake, BMI, physical activity, postmenopausal status, current smoking, hypertension. q-value, false discovery rate adjusted p-value

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