Table 1 Demographic, genetic, and neuropsychological characteristics of the participants

Demographic characteristics

 Age^a

67.30 ± 6.50

72.34 ± 4.96^**

 Female, n (%)^b

37 (74)

30 (48.4)^*

 Education, years^a

16.12 ± 2.32

15.27 ± 2.89

Genetic characteristics

 APOE e4 + , n (%)

–

45 (72.6)^†

 BDNF Met + , n (%)

–

20 (32.3)^††

Neuropsychological characteristics

 MMSE, score^a

29.16 ± 0.87

25.48 ± 2.45^**

 RAVLT 1–5, score^a

56.28 ± 7.72

32.52 ± 8.24^**

 RAVLT delayed recall, score^a

11.84 ± 2.10

2.81 ± 3.03^**

 LM delayed recall, score^a

17.48 ± 3.21

3.81 ± 4.31^**

 ROCF recall, score^a

19.82 ± 6.30

6.70 ± 5.65^**

 ROCF copy, score^a

31.09 ± 2.93

26.33 ± 6.86^**

 Digit span, score^a

14.04 ± 4.49

14.03 ± 3.61

 TMT A, time to completion (s)^a

39.15 ± 12.59

57.50 ± 29.69^**

 TMT B, time to completion (s)^a

77.86 ± 25.08

173.77 ± 84.76^**

 PST^a

26.84 ± 6.40

47.42 ± 22.91^**

 P-VF, score^a

51.14 ± 12.28

40.35 ± 11.86^**

 C-VF animals, score^a

27.88 ± 5.61

18.48 ± 4.94^**

 BNT-30, errors after a semantic cue^a

1.42 ± 2.00

4.65 ± 3.00^**