Table 1 Participant characteristics (mean ± SD or N(%)) by APOE genotype for all subjects and cognitively normal subjects

Age (years)

77.4 ± 8.1

76.8 ± 7.2

75.8 ± 6.1

F(2,221) = 0.72, p = 0.49

77.4 ± 8.1

76.4 ± 7.1

75.4 ± 5.6

F(2,188) = 0.74, p = 0.48

Sex (women)

N = 12 (55%)

N = 73 (57%)

N = 44 (59%)

X²(2) = 0.21, p = 0.90

N = 12 (55%)

N = 70 (60%)

N = 37 (70%)

X²(2) = 2.03, p = 0.36

Education (years)

14.8 ± 2.1

15.5 ± 2.3

16.0 ± 2.5

F(2,221) = 2.15, p = 0.12

14.8 ± 2.1

15.3 ± 2.2

15.5 ± 2.4

F(2,188) = 0.71, p = 0.49

SBP

125.2 ± 21.8

125.3 ± 14.8

129.3 ± 17.9

F(2,215) = 1.38, p = 0.25

125.2 ± 21.8

125.5 ± 15.2

130.0 ± 18.8

F(2,182) = 1.29, p = 0.28

DBP

70.7 ± 11.7

71.5 ± 9.2

75.0 ± 9.3*

F(2,215) = 3.49, p = 0.03

70.7 ± 11.7

71.5 ± 9.1

75.4 ± 9.0*

F(2,182) = 3.43, p = 0.03

BMI

25.7 ± 3.6

25.8 ± 4.3

25.0 ± 3.6

F(2,217) = 0.90, p = 0.41

25.6 ± 3.6

25.7 ± 4.1

25.1 ± 3.7

F(2,184) = 0.38, p = 0.68

Diabetes

N = 4 (18%)

N = 19 (15%)

N = 9 (12%)

X²(2) = 0.59, p = 0.74

N = 4 (18%)

N = 16 (14%)

N = 6 (11%)

X²(2) = 0.63, p = 0.73

Cognitively impaired

0 (0%)

12 (9%)

21 (28%)

X²(2) = 17.86, p < 0.001