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Table 7 Comparison of selected MRI volumes between AD patients with SEA and those without

From: Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method

 

SEA (n = 13)

No SEA (n = 25)

P-value

Frontal cortex volume left (ml)

105.0 [100.5;111.98]

97.4 [93.2;102.9]

0.038

Temporal cortex volume (ml)

132.2 [125.2;137.2]

122.5 [112.0;131.0]

0.041

Temporal cortex volume left (ml)

67.9 [62.6;69.4]

62.2 [54.2;63.8]

0.041

Enthorinal cortex volume (ml)

5.3 [4.9;5.6]

4.6 [4.0;5.1]

0.027

Enthorinal cortex volume left (ml)

2.6 [2.5;2.8]

2.4 [2.1;2.5]

0.041

Enthorinal cortex volume right (ml)

2.6 [2.3;2.8]

2.3 [2.0;2.5]

0.032

FLAIR hyperintensity volume (ml)

9.4 [4.4;14.2]

4.0 [2.6;15.7]

0.524

FLAIR hyperintensity volume, posterior region (ml)

2.9 [1.5;6.8]

2.0 [0.9;8.5]

0.381

FLAIR hyperintensity volume, posterior periventricular region (ml)

2.5 [1.4;6.5]

1.95 [0.85;8.1]

0.541

T1 hypointensity volume (ml)

3.0 [2.2;6.2]

3.2 [2.6;8.4]

0.590

  1. FLAIR hyperintensity volume and T1 hypointensity volume were not significantly different but are shown as well. Data is reported as median with IQR [Q1,Q3]. P-values were calculated with Mann–Whitney U test
  2. Significance level was set at 0.05
  3. FLAIR hyperintensity volumes were missing in 5 patients with SEA and in 6 patients without SEA. All volumes were missing in 3 patients without SEA
  4. FLAIR Fluid Attenuated Inversion Recovery