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Table 6 Neuropsychological test results of AD patients with SEA versus those without SEA

From: Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method

 

SEA (n = 13)

No SEA (n = 28)

P-value

ACE-R

76 [69;83]

75 [72;79]

0.948

ACE-R Orientation

9.5 [9;10]

9 [8;10]

0.211

ACE-R Concentration

5 [4.25;5]

5 [5;5]

0.244

ACE-R Memory

19 [16;20]

17 [16;20.75]

0.742

ACE-R Fluency

6 [3;8]

5 [3;9.5]

1.000

ACE-R Language

26 [24;26]

25.5 [22;26]

0.760

ACE-R Praxis

5 [4.25;8]

7 [6;7]

0.648

ACE-R Perception

8 [7;8]

8 [8;8]

0.257

MMSE

27 [24;28]

26 [25;27.25]

0.854

TMT-A

51 [35;72.5]

44 [30;63.5]

0.367

TMT-B

150 [109.5; > 300]

146 [117; > 300]

0.985

RBANS

80 [62.75;84]

78 [72.5;82.5]

0.868

RBANS Immediate Memory

85 [66;87]

69 [61;73]

0.101

RBANS Visuospatial

92 [84.75;108]

112 [102;116]

0.009

RBANS Language

87.5 [82;91.5]

89 [83.25;92]

0.811

RBANS Attention

77 [66.75;85.75]

86.5 [79;91.75]

0.050

RBANS Delayed Memory

64 [54;82.5]

58 [47;71.25]

0.314

GDeprS

7 [5;10]

7 [3.25;11.75]

0.635

PSQI

3 [1;8.25]

7.5 [1.75;13.25]

0.485

  1. Data is reported as median with IQR [Q1,Q3] or number as appropriate. P-values were calculated with Fisher’s-exact and Mann–Whitney U test
  2. Significance level was set at 0.05. Total ACE-R, ACE-R memory, ACE-R Fluency, ACE-R Language and ACE-R Perception values were missing in 4 patients with and 6 patients without SEA, ACE-R Orientation, ACE-R Concentration and ACE-R Praxis were missing in 3 patients with and 6 patients without SEA, TMT values in 2 patients with and 5 patients without SEA RBANS values in 3 patients with and 12 patients without SEA, GDeprS in 2 patients with and 10 patients without SEA and PSQI in 1 patient with and 2 patients without SEA
  3. MMSE Mini Mental State Examination, ACE-R Addenbrooke’s Cognitive Examination—Revised, RBANS Repeatable Battery of the Assessment of Neuropsychological Status, GDeprS Geriatric Depression Scale, PSQI Pittsburgh Sleep Quality Index
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Alzheimer's Research & Therapy

ISSN: 1758-9193