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Table 5 Clinical characterisation of AD patients with SEA and those without

From: Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method

 

SEA (n = 13)

No SEA (n = 28)

P-value

Age at NPT

68 [67;75]

71 [68;73.25]

0.448

Age at disease onset

65 [61;72]

68 [65;71.5]

0.448

Disease duration (years)

3 [3;4]

3 [2;4]

0.678

Education duration (years)

16 [12;17]

14 [10.5;15]

0.167

Female sex

7 (54%)

13 (46%)

0.744

Arterial hypertension

5 (38%)

15 (54%)

0.505

Dyslipidemia

11 (85%)

20 (71%)

0.458

Smoking

1 (8%)

3 (11%)

1.000

Diabetes mellitus

2 (15%)

2 (7%)

0.579

Anti-AD medication

10 (77%)

26 (93%)

0.304

Sleep medication

3 (23%)

9 (32%)

0.719

Antidepressants

5 (38%)

10 (36%)

1.000

TST (hours)

8.25 [7;8.87]

8.125 [6.8125;9]

0.900

Time to sleep onset (minutes)

10 [5;15]

15 [8.125;17.25]

0.347

  1. Data is reported as median with IQR [Q1,Q3] or number as appropriate. P-values were calculated with Fisher’s exact and Mann–Whitney U test. Significance level was set at 0.05
  2. TST total sleep time, TST and time to sleep onset were missing in 1 patient with and 2 patients without SEA